Django is a very robust, effective framework, and is used (and therefore battle-tested) by some of the largest websites in the world. Mozilla uses it for a number of its websites, and it’s also used by Pinterest, Instagram, and the Onion, to name just a few. It’s very popular and, crucially, under active development. It doesn’t matter what operating system you’re using, either – Windows, Mac, Linux – it’s all the same to Django.